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FINBIONE SCIENTIFIC

Pre-Clinical

Early-stage research services including pharmacology, toxicology, and proof-of-concepts studies

In Vitro

Cytotoxicity & Viability Assays

Assessment of compound-induced cell toxicity and viability using standardized in vitro models to support early safety evaluation.

Cell Proliferation & Cell-Cycle

Analysis of cell growth patterns and cell-cycle progression to understand compound effects on cellular replication.

Regulated Cell Death & DNA Damage

Evaluation of apoptosis, necrosis, and DNA damage responses to determine cellular stress and damage mechanisms.

Migration, Invasion & Wound Healing

In vitro assays to study cell migration and invasion behavior relevant to cancer metastasis and tissue repair.

3D Systems

Advanced three-dimensional cell culture models that better mimic in vivo tissue architecture and function.

Angiogenesis Assays

Assessment of pro- and anti-angiogenic activity by measuring endothelial cell growth and tube formation.

Protein Characterization

Qualitative and quantitative analysis of protein expression, structure, and functional activity in cell systems.

Molecular Biology

DNA Extraction

Isolation of high-quality genomic DNA from biological samples for downstream molecular applications.

RNA Extraction

Purification of intact RNA to support gene expression analysis and transcriptomic studies.

qPCR

Quantitative PCR analysis for accurate measurement of DNA targets across multiple sample types.

RT-qPCR

Reverse transcription quantitative PCR for sensitive detection and quantification of RNA expression levels.

SNP Profiling

Genetic variation analysis through single nucleotide polymorphism profiling for research and biomarker studies.

In Vitro Assays Disease-Focused Models

Cancer

Cell-based functional assays to evaluate anticancer activity, signaling pathways, and cellular response.

Cardiovascular

Assessment of compound effects on cardiac cell function, contractility, and viability.

Respiratory

Functional assays using airway and lung cell models to study respiratory efficacy and toxicity.

Immunomodulatory & Inflammation

Cell-based evaluation of immune activation, cytokine release, and inflammatory signaling pathways.

Neurological

Functional neuronal cell assays to assess neuroactivity, neuroprotection, and cytotoxicity.

Metabolic

Cell-based metabolic assays to evaluate insulin signaling, glucose uptake, and lipid metabolism.

Musculoskeletal

Functional assays using muscle and bone cell models to study differentiation and cellular performance.

ROS & Oxidative Stress

Measurement of intracellular reactive oxygen species and antioxidant response in cell-based systems.

Dermatology & Cosmetics

Skin and cosmetic cell-based assays to evaluate safety, irritation, and biological performance.

Microbiology & Antimicrobial

Total Aerobic Count

Enumeration of aerobic microorganisms to assess overall microbial load in test samples.

Total Microbial / Fungal Count

Quantification of total bacterial and fungal populations to ensure microbiological quality.

Specific Pathogen Detection

Targeted identification of specific pathogenic microorganisms using validated detection methods.

Preservative Effectiveness Test

Evaluation of preservative systems to confirm their ability to control microbial growth over time.

Bacterial Endotoxin Test

Detection and quantification of endotoxins to ensure product safety and regulatory compliance.

Antimicrobial Susceptibility Testing

Assessment of microbial sensitivity or resistance to antimicrobial agents.

Fungicidal Activity

Evaluation of antifungal efficacy against selected fungal strains under controlled conditions.

Anti-Biofilm Formation Assay

Measurement of a compound’s ability to prevent or disrupt microbial biofilm formation.

Genotypic Assay

Molecular identification and characterization of microorganisms based on genetic markers.

Pharmacokinetics & Pharmacodynamics

Microbiological assessment supporting drug absorption, distribution, and biological activity studies.

Toxicity Assessment

Basal Cytotoxicity

Initial screening of compound toxicity using general cell viability and cytotoxicity endpoints.

Cardiotoxicity

Evaluation of potential adverse effects on cardiac cells and functional cardiac markers.

Eye Irritation

In vitro assessment of ocular irritation potential using alternative test models.

Hepatotoxicity

Assessment of liver-specific toxicity through hepatocyte-based in vitro models.

Neurotoxicity

Evaluation of compound effects on neuronal cells and neuro-specific toxicity markers.

Pyrogenicity Testing

Detection of pyrogenic responses to assess fever-inducing potential of test substances.

Respiratory Tract Toxicity

Assessment of toxic effects on respiratory epithelial cells and airway models.

Reproductive Toxicity

Evaluation of potential adverse effects on reproductive cells and related biological pathways.

Skin Irritation

In vitro testing to assess irritation potential on reconstructed human skin models.

Skin Sensitisation & Allergic Contact Dermatitis

Assessment of sensitization potential to identify compounds that may trigger allergic skin reactions.

Genotoxicity / Mutagenicity

Evaluation of DNA damage and mutation potential to assess genetic safety risks.

In Vivo Assays

Cancer

In vivo tumor models used to evaluate antitumor efficacy, disease progression, and therapeutic response.

Cardiovascular

Animal models to assess cardiovascular function, safety, and efficacy of investigational compounds.

Immunomodulatory & Inflammation

Evaluation of immune response modulation and anti-inflammatory activity using validated in vivo models.

Respiratory

In vivo respiratory disease models to study airway function, inflammation, and pulmonary safety.

Neurological

Assessment of neuroprotective and neurotoxic effects using behavior and disease-relevant animal models.

Metabolic

Metabolic disease models for evaluating glucose regulation, lipid metabolism, and systemic energy balance.

Musculoskeletal

In vivo models to study bone, muscle, and joint disorders, including efficacy and functional recovery.

ROS & Oxidative Stress

Assessment of oxidative stress markers and antioxidant activity in relevant animal models.

Genotoxicity

In vivo evaluation of DNA damage and genetic safety to support regulatory toxicology requirements.