Our advanced microbiology in vitro assays provide comprehensive solutions for microbial detection, characterization, and antimicrobial evaluation, integrating classical microbiology with cutting-edge molecular and functional approaches.
State-of-the-art microbial identification integrates classical microbiology with innovative molecular approaches to achieve high sensitivity, specificity, and speed.
Selective and differential media remain indispensable for isolating bacteria, fungi, and parasites. Colony morphology, pigmentation, and hemolysis patterns guide initial classification. Automated biochemical platforms such as VITEK and API systems allow rapid phenotypic profiling, minimizing operator variability.
Quantitative PCR is a gold standard for detecting pathogen-specific DNA/RNA sequences, enabling detection of fastidious or non-culturable organisms within hours. Emerging methods include multiplex PCR panels and next-generation sequencing (NGS) for comprehensive pathogen and resistance gene profiling.
Gram staining, acid-fast staining, calcofluor white, and fluorescent in situ hybridization (FISH) offer rapid visualization cues, essential in differentiating microbial classes and assessing cell viability.
Modern AST combines classical methods with innovative technologies for precise therapeutic guidance.
Utilizing broth microdilution or agar dilution, these quantitative assays provide critical data on antimicrobial potency, distinguishing bacteriostatic versus bactericidal activity.
Standardized qualitative and semi-quantitative methods remain standard for routine clinical use, with E-test strips offering accurate MIC values on agar plates through antibiotic gradients.
Integration of robotics and digital imaging accelerates susceptibility testing, supporting multiplexed assessments and real-time data analysis.
Understanding genetic resistance mechanisms is paramount in managing antimicrobial resistance (AMR).
PCR-based assays quickly detect key resistance genes (e.g., ESBLs, carbapenemases). Multiplex platforms allow simultaneous detection of multiple genes.
Restriction Fragment Length Polymorphism helps characterize plasmid-borne resistance and track transmission events. Conjugation assays elucidate horizontal gene transfer potential.
CRISPR-based diagnostics and targeted nanopore sequencing enhance rapid resistance gene detection and surveillance.
Efficient pathogen screening across pathogen types employs tailored high-sensitivity methods.
Combines culture on chromogenic/specialized media, serological assays (e.g., galactomannan), and PCR for identification and antifungal susceptibility.
Real-time PCR and antigen detection kits enable rapid viral load estimation and screening for diverse viruses, with emerging multiplex viral panels enhancing throughput.
Microscopic examination remains gold standard for many parasites, complemented by serological and nucleic acid tests increasing detection sensitivity and specificity.
Recent advancements include 3D in vitro microbial models mimicking host environments, organ-on-chip systems integrating microbiota-host interactions, and AI-driven assay optimization enhancing predictive accuracy for antimicrobial efficacy and resistance evolution.
These advances promise to bridge in vitro findings with clinical outcomes more effectively.
Comprehensive microbial detection and characterization using state-of-the-art technologies.
Cutting-edge antimicrobial susceptibility testing for precise therapeutic guidance.
Advanced molecular tools for resistance profiling and surveillance.
Tailored fungal, viral, and parasitic screening with high sensitivity and specificity.
Innovative 3D models and AI-driven optimization bridging in vitro findings with clinical outcomes.
