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Cytotoxicity & Viability Assays

Cytotoxicity & Viability Assays: Precision Insights into Cellular Health

Delivering cutting-edge cellular analyses to accelerate drug discovery, toxicological safety, and biomedical research, our cytotoxicity and viability assay suite combines sensitivity, scalability, and mechanistic depth.

Metabolic Activity Assays: MTT, MTS, XTT, WST-1, CCK-8

We provide a comprehensive panel of mitochondrial metabolic assays—MTT, MTS, XTT, WST-1, and CCK-8—each designed to measure cellular metabolic activity as a direct proxy for viability.

These assays generate reproducible quantitative signals correlating with metabolically active cells, optimized for diverse cell types and high-throughput workflows.

Membrane Integrity & Lysosomal Function: LDH Release and Neutral Red Uptake

LDH release assays measure plasma membrane disruption by detecting enzymatic LDH release upon cytotoxic insult.

Neutral Red uptake quantifies lysosomal membrane integrity and endocytic activity, revealing sub-lethal stress often missed by traditional viability stains.

ATP-Based Viability: CellTiter-Glo Luminescence Assay

Our CellTiter-Glo luminescent assay uses ATP as a surrogate for live cell quantification.

Its luciferase-based reaction provides rapid, ultrasensitive detection ideal for real-time monitoring of drug effects.

Live-Dead Discrimination: Alamar Blue, Trypan Blue, PI/DRAQ7

Alamar Blue enables non-destructive metabolic monitoring.

Trypan Blue exclusion provides rapid manual viability measurement.

PI and DRAQ7 dyes precisely identify compromised cells through membrane permeability detection.

Real-Time, Label-Free Cytotoxicity: xCELLigence & ECIS

Our impedance-based systems—xCELLigence and ECIS—offer label-free continuous measurement of cell adhesion, proliferation, and morphology changes in real time.

These provide unmatched temporal resolution for understanding drug mechanisms.

Cytotoxicity & Viability Assays

Why Partner With Us for Cytotoxicity & Viability Testing?

Advanced, multiparametric assays with both endpoint and kinetic insights.

High-throughput & scalable workflows for discovery to regulatory research.

Expertise with mammalian, stem-cell derived, primary, and engineered cell systems.

GLP/GxP aligned standardized and validated protocols.

AI-driven image analytics ensuring precision and reproducibility.

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