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Developmental, Endocrine, & Reproductive Toxicity Testing

Integrated Classical and New Approaches

Our developmental, endocrine, and reproductive toxicity testing services integrate classical methodologies with cutting-edge approaches to provide comprehensive insights into potential toxicological effects on development and reproduction. These platforms are critical for regulatory compliance and advancing human-relevant safety assessments.

Embryotoxicity and Stem Cell Fate Assays

Modern developmental toxicity testing increasingly utilizes pluripotent stem cell-based systems to model early embryogenesis and predict teratogenic effects:

Hormone Receptor and Enzymatic Endpoint Assays

Endocrine and reproductive toxicity assessment centers on key molecular targets involved in hormonal signaling:

Adverse Outcome Pathway (AOP)-Based Frameworks

AOP-driven testing provides mechanistic links from molecular initiating events to organismal adverse outcomes:

Emerging New Approach Methodologies (NAMs) for DART

Emerging NAMs are transforming developmental and reproductive toxicity testing by enhancing human relevance and reducing reliance on animal models:

Developmental, Endocrine, & Reproductive Toxicity Testing
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