Our immunotoxicity and effector response platforms offer comprehensive, mechanistic insights into immune cell modulation, cytokine dynamics, and antibody effector functions crucial for the development and safety evaluation of immunomodulatory therapeutics, vaccines, and biologics.
We evaluate the proliferation, activation, and functional status of T and B lymphocytes using multiparametric flow cytometry, ELISPOT, and cytokine secretion assays. This enables precise assessment of immunomodulatory effects and potential immunotoxicity at the cellular level.
Using advanced multiplex immunoassays, we quantify broad panels of cytokines, chemokines, and growth factors from biological samples, providing detailed immune response profiles and early detection of pro-inflammatory or immunosuppressive signals.
Our functional cell-based assays measure the capacity of therapeutic antibodies or immune complexes to recruit natural killer cells and complement components, eliciting cytotoxic responses essential for both efficacy and safety assessments.
We perform sensitive detection and quantification of anti-drug antibodies (ADA) to evaluate immunogenicity risk. Additionally, our assays assess cytokine storm potential by monitoring key inflammatory mediators, aiding in the prediction and mitigation of adverse immune reactions.
Integrated cellular and humoral immune function assays for comprehensive immunotoxicity profiling.
High-throughput, multiplexed cytokine detection offering nuanced immune landscape analysis.
Validated ADCC and CDC assays providing functional antibody activity assessment.
Sensitive ADA assays coupled with cytokine storm risk evaluation.
Expert data analysis, scientific consultation, and regulatory-compliant reporting.
