Protein & Enzyme Characterization

Our protein and enzyme characterization suite offers a comprehensive array of cutting-edge analytical techniques essential for the detailed understanding, development, and quality control of biologics and enzymes across discovery and clinical development.

We conduct high-resolution protein separation and identification using SDS-PAGE, followed by sensitive immunodetection via Western blotting, allowing precise confirmation of protein identity and post-translational modifications.

Our versatile ELISA platforms (direct, sandwich, competitive) provide quantitative measurement of proteins or antibodies with high specificity and dynamic range.

Our expertise covers multi-modal protein purification workflows employing affinity tags, ion-exchange, and size-exclusion methods to isolate highly pure, functional proteins essential for downstream characterization, structural studies, and functional assays.

These scalable processes support both tagged and native protein targets from diverse expression systems.

We elucidate protein-protein and protein-DNA interactions using advanced assays like Co-IP, ChIP-qPCR, pull-down, and EMSA.

These techniques reveal molecular interaction networks, transcription factor binding, and regulatory mechanics, crucial for drug target validation and mechanistic biology.

Our enzyme kinetics platforms provide detailed measurements of catalytic activity, substrate specificity, and inhibitor effects using adaptable readouts—colorimetric, fluorescent, or luminescent—to suit various assay needs including high-throughput screening.

We apply state-of-the-art mass spectrometry and proteomics workflows to map critical PTMs such as phosphorylation, ubiquitination, and acetylation.

These analyses are vital for understanding regulation, signaling pathways, and biomarker discovery in drug development.